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ING5

Official Full Name
inhibitor of growth family, member 5
Background
The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent regulatory pathway.
Synonyms
ING5; inhibitor of growth family, member 5; inhibitor of growth protein 5; FLJ23842; p28ING5; 1700001C14Rik; 1700027H23Rik; 1810018M11Rik; ING 5; ING-5; Inhibitor of growth family member 5; p28 ING 5; p28 ING-5; p28 ING5

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