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HEXA


Official Full Name
hexosaminidase subunit alpha
Organism
Homo sapiens
Gene ID
3073
Background
This gene encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta-hexosaminidase. This enzyme, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons, the underlying cause of neurodegenerative disorders termed the GM2 gangliosidoses, including Tay-Sachs disease (GM2-gangliosidosis type I). Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
Synonyms
TSD

Cat.No. Product Name Price
SHH119117 shRNA set against Mouse Hexa(NM_010421.4) Inquiry
SHH119153 shRNA set against Rat Hexa(NM_001004443.1) Inquiry
SHH311765 shRNA set against Human HEXA (NM_000520.4) Inquiry
SHH311769 shRNA set against Mouse HEXA (NM_010421.4) Inquiry
SHH311773 shRNA set against Rat HEXA (NM_001004443.1) Inquiry
SHW001189 shRNA set against Chicken HEXA (NM_001030390) Inquiry
SHW012367 shRNA set against Danio rerio HEXA (NM_001114845) Inquiry
Cat.No. Product Name Price
CDFR001436 Rat Hexa cDNA Clone(NM_001004443.1) Inquiry
MiUTR1M-05607 HEXA miRNA 3'UTR clone Inquiry
MiUTR1R-02423 HEXA miRNA 3'UTR clone Inquiry
MiUTR3H-08787 HEXA miRNA 3'UTR clone Inquiry
CDCB160294 Human HEXA ORF clone (NM_000520) Inquiry
CDCB162664 Chicken HEXA ORF Clone (NM_001030390) Inquiry
CDCB173842 Danio rerio HEXA ORF Clone (NM_001114845) Inquiry
CDCB180988 Rabbit HEXA ORF clone (XM_002717700.2) Inquiry
CDCG013751 Mouse HEXA ORF clone(NM_010421.4) Inquiry
CDCR368357 Rat Hexa ORF Clone(NM_001004443.1) Inquiry
CDCS405719 Human HEXA ORF Clone (BC018927) Inquiry
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