Tel: 1-631-626-9181 (USA)   44-207-097-1828 (Europe)


Official Full Name
hepcidin antimicrobial peptide
The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq, Jul 2008]
HAMP; hepcidin antimicrobial peptide; HEPC; PLTR; HFE2B; LEAP1; hepcidin; putative liver tumor regressor; liver-expressed antimicrobial peptide 1; LEAP 1; hamp1; hamp2; hepcidin-1; hepcidin-2; preprohepcidin 1; iron regulatory peptide; hepcidin antimicrobial peptide 1; hepcidin antimicrobial peptide 2

Interested in learning more?

Contact us today for a free consultation with the scientific team and discover how Creative Biogene can be a valuable resource and partner for your organization.

Request a quote today!