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HAMP


Official Full Name
hepcidin antimicrobial peptide
Organism
Homo sapiens
Gene ID
57817
Background
The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity against bacteria and fungi. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq, Oct 2014]
Synonyms
HEPC; PLTR; HFE2B; LEAP1

Cat.No. Product Name Price
SHH310213 shRNA set against Human HAMP (NM_021175.2) Inquiry
SHW014294 shRNA set against Danio rerio HAMP (NM_001289794) Inquiry
SHW017509 shRNA set against Danio rerio HAMP (NM_205583) Inquiry
Cat.No. Product Name Price
CDCR306732 Human HAMP ORF Clone(NM_021175.2) Inquiry
CDCS415305 Human HAMP ORF Clone (BC020612) Inquiry
CDFG001630 Human HAMP cDNA Clone(NM_021175.2) Inquiry
MiUTR1H-04369 HAMP miRNA 3'UTR clone Inquiry
CDCB175769 Danio rerio HAMP ORF Clone (NM_001289794) Inquiry
CDCB178984 Danio rerio HAMP ORF Clone (NM_205583) Inquiry
CDCB182205 Rabbit HAMP ORF clone (XM_008249495.1) Inquiry
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