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CACNB4


Official Full Name
calcium voltage-gated channel auxiliary subunit beta 4
Organism
Homo sapiens
Gene ID
785
Background
This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE), juvenile myoclonic epilepsy (JME), and episodic ataxia, type 5. [provided by RefSeq, Aug 2016]
Synonyms
EA5; EJM; CAB4; EIG9; EJM4; EJM6; CACNLB4

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SHG132013 shRNA set against Mouse Cacnb4(NM_001037099.1) Inquiry
SHG132049 shRNA set against Mouse Cacnb4(NM_146123.2) Inquiry
SHH253453 shRNA set against Human CACNB4 (NM_000726.3) Inquiry
SHH253457 shRNA set against Mouse CACNB4 (NM_146123.2) Inquiry
SHH253461 shRNA set against Rat CACNB4 (NM_001105733.1) Inquiry
SHW000078 shRNA set against Chicken CACNB4 (NM_001001733) Inquiry
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OE-PNDC000458 Human CACNB4 Nanodisc Inquiry
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CDFH002585 Human CACNB4 cDNA Clone(NM_001145798.1) Inquiry
CDFR005469 Rat Cacnb4 cDNA Clone(NM_001105733.1) Inquiry
MiUTR1M-02447 CACNB4 miRNA 3'UTR clone Inquiry
MiUTR1M-02448 CACNB4 miRNA 3'UTR clone Inquiry
CDCB161553 Chicken CACNB4 ORF Clone (NM_001001733) Inquiry
CDCB166334 Chicken CACNB4 ORF Clone (NM_204344) Inquiry
CDCB191196 Rabbit CACNB4 ORF clone (XM_008258582.1) Inquiry
CDCR040628 Human CACNB4 ORF clone (NM_001145798.1) Inquiry
CDCR040632 Mouse Cacnb4 ORF clone (NM_146123.2) Inquiry
CDCR040634 Mouse Cacnb4 ORF clone (NM_001037099.1) Inquiry
CDCR372515 Rat Cacnb4 ORF Clone(NM_001105733.1) Inquiry
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