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C8B


Official Full Name
complement C8 beta chain
Organism
Homo sapiens
Gene ID
732
Background
This gene encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
Synonyms
C82

Cat.No. Product Name Price
SHG128773 shRNA set against Human C8B(NM_000066.2) Inquiry
SHG128827 shRNA set against Mouse C8b(NM_133882.2) Inquiry
SHH252593 shRNA set against Human C8b (NM_000066.2) Inquiry
SHH252597 shRNA set against Mouse C8b (NM_133882.2) Inquiry
SHW014078 shRNA set against Danio rerio C8B (NM_001256723) Inquiry
Cat.No. Product Name Price
CDCG012403 Rat C8B ORF clone(NM_001191759.1) Inquiry
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MiUTR1H-01494 C8B miRNA 3'UTR clone Inquiry
MiUTR1M-02405 C8B miRNA 3'UTR clone Inquiry
CDCB159553 Human C8B ORF clone (BC130575) Inquiry
CDCB175553 Danio rerio C8B ORF Clone (NM_001256723) Inquiry
CDCB181056 Rabbit C8B ORF clone (NM_001082668.1) Inquiry
CDCG012402 Mouse C8B ORF clone(NM_133882.2) Inquiry
CDCR278238 Human C8B ORF Clone(NM_000066.2) Inquiry
CDCS405391 Human C8B ORF Clone (BC130575) Inquiry
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