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APOH


Official Full Name
apolipoprotein H
Organism
Homo sapiens
Gene ID
350
Background
Apolipoprotein H, also known as beta-2-glycoprotein I, is a component of circulating plasma lipoproteins. It has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, hemostasis, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome (APS). The anti-beta (2) glycoprotein I antibodies from APS patients, mediate inhibition of activated protein C which has anticoagulant properties. Because beta-2-GPI is the main autoantigen in patients with APS, the disruption of this pathway by autoantibodies may be an important mechanism for thrombosis in patients with APS.[provided by RefSeq, Dec 2019]
Synonyms
BG; B2G1; B2GP1

Cat.No. Product Name Price
SHG065881 shRNA set against Human APOH(NM_000042.2) Inquiry
SHG066013 shRNA set against Mouse Apoh(NM_013475.4) Inquiry
SHG066031 shRNA set against Rat Apoh(NM_001009626.1) Inquiry
SHH238566 shRNA set against Human APOH (NM_000042.2) Inquiry
SHH238574 shRNA set against Rat APOH (NM_001009626.1) Inquiry
SHW004221 shRNA set against Chicken APOH (NM_001277994) Inquiry
Cat.No. Product Name Price
CDFR002215 Rat Apoh cDNA Clone(NM_001009626.1) Inquiry
MiUTR1H-00481 APOH miRNA 3'UTR clone Inquiry
MiUTR1M-01591 APOH miRNA 3'UTR clone Inquiry
MiUTR1R-00312 APOH miRNA 3'UTR clone Inquiry
CDCB165696 Chicken APOH ORF Clone (NM_001277994) Inquiry
CDCB194071 Rabbit APOH ORF clone (XM_002719215.2) Inquiry
CDCL182728 Human APOH ORF clone(NM_000042.2) Inquiry
CDCL182729 Mouse APOH ORF clone(NM_013475.4) Inquiry
CDCR369227 Rat Apoh ORF Clone(NM_001009626.1) Inquiry
CDCS405373 Human APOH ORF Clone (BC020703) Inquiry
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