Official Full Name

ADP-ribosylation factor-like 6

Background

The protein encoded by this gene belongs to the ARF family of GTP-binding proteins. ARF proteins are important;regulators of cellular traffic and are the founding members of an expanding family of homologous proteins and genomic;sequences. They depart from other small GTP-binding proteins by a unique structural device that implements front-back;communication from the N-terminus to the nucleotide-binding site. Studies of the mouse ortholog of this protein;suggest an involvement in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation.Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been described.

Synonyms

ARL6; ADP-ribosylation factor-like 6; BBS3, RP55; zgc:101762; ADP-ribosylation factor-like protein 6; bbs3