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ARHGEF15

Official Full Name
Rho guanine nucleotide exchange factor (GEF) 15
Background
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein-coupled receptors. This gene encodes a protein that functions as a specific guanine nucleotide exchange factor for RhoA. It also interacts with ephrin A4 in vascular smooth muscle cells. Two alternatively spliced transcripts variants that encode the same protein have been found for this gene.
Synonyms
ARHGEF15; Rho guanine nucleotide exchange factor (GEF) 15; rho guanine nucleotide exchange factor 15; ARGEF15; FLJ13791; KIAA0915; MGC44868; Rho guanine exchange factor (GEF) 15; Vsm RhoGEF; ephexin-5; Rho GEF 15; E5; Ephexin5; Vsm-RhoGEF

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