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ANKS1B

Official Full Name
ankyrin repeat and sterile alpha motif domain containing 1B
Organism
Homo sapiens
GeneID
56899
Background
This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene. [provided by RefSeq, Aug 2011]
Synonyms
EB1; AIDA; EB-1; ANKS2; AIDA-1; cajalin-2;

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