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ALG1

Official Full Name
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
Background
The enzyme encoded by this gene catalyzes the first mannosylation step in the biosynthesis of lipid-linked oligosaccharides. This gene is mutated in congenital disorder of glycosylation type Ik.
Synonyms
ALG1; asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog (S. cerevisiae); asparagine linked glycosylation 1 homolog (yeast, beta 1,4 mannosyltransferase); chitobiosyldiphosphodolichol beta-mannosyltransferase; HMAT1; HMT 1; 4-mannosyltransferase; ALG1_HUMAN; asparagine-linked glycosylation 1 homolog (yeast, beta-1,4-mannosyltransferase); Asparagine-linked glycosylation protein 1 homolog; Beta 1 4 mannosyltransferase; Beta-1; CDG1K; GDP Man GlcNAc2 PP dolichol mannosyltransferase; GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase; GDP-mannose-dolichol diphosphochitobiose mannosyltransferase; Hmat-1; HMT1; Mannosyltransferase 1; Mannosyltransferase-1; MT 1; MT-1; MT1; OTTHUMP00000159923; beta-1,4 mannosyltransferase; beta-1,4-mannosyltransferase; HMT-1; Mat-1; ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase; zgc:66221; wu:fi34b12

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