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ALDOB


Official Full Name
aldolase, fructose-bisphosphate B
Organism
Homo sapiens
Gene ID
229
Background
Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. [provided by RefSeq, Dec 2008]
Synonyms
ALDB; ALDO2

Cat.No. Product Name Price
SHG053281 shRNA set against Rat Aldob(NM_012496.2) Inquiry
SHG053335 shRNA set against Mouse Aldob(NM_144903.2) Inquiry
SHH235018 shRNA set against Human ALDOB (NM_000035.3) Inquiry
SHH235022 shRNA set against Mouse ALDOB (NM_144903.2) Inquiry
SHH235026 shRNA set against Rat ALDOB (NM_012496.2) Inquiry
SHW000759 shRNA set against Chicken ALDOB (NM_001007977) Inquiry
SHW015604 shRNA set against Danio rerio ALDOB (NM_194367) Inquiry
Cat.No. Product Name Price
CDCR377405 Rat Aldob ORF Clone(NM_012496.2) Inquiry
CDFR010174 Rat Aldob cDNA Clone(NM_012496.2) Inquiry
MiUTR1M-01402 ALDOB miRNA 3'UTR clone Inquiry
MiUTR1R-00226 ALDOB miRNA 3'UTR clone Inquiry
MiUTR3H-12566 ALDOB miRNA 3'UTR clone Inquiry
CDCB162234 Chicken ALDOB ORF Clone (NM_001007977) Inquiry
CDCB177079 Danio rerio ALDOB ORF Clone (NM_194367) Inquiry
CDCB180472 Rabbit ALDOB ORF clone (NM_001171114.1) Inquiry
CDCL182663 Human ALDOB ORF clone(NM_000035.3) Inquiry
CDCR026688 Mouse Aldob ORF clone (NM_144903.2) Inquiry
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