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AKR1C2


Official Full Name
aldo-keto reductase family 1 member C2
Organism
Homo sapiens
Gene ID
1646
Background
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Synonyms
DD; DD2; TDD; BABP; DD-2; DDH2; HBAB; HAKRD; MCDR2; SRXY8; DD/BABP; AKR1C-pseudo

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SHH234550 shRNA set against Mouse AKR1C2 (NM_029901.2) Inquiry
SHH234554 shRNA set against Rat AKR1C2 (NM_001013057.1) Inquiry
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CDCB159327 Human AKR1C2 ORF clone (BC007024) Inquiry
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CDCR369785 Rat Akr1c2 ORF Clone(NM_001013057.1) Inquiry
CDCS408076 Human AKR1C2 ORF Clone (BC007024) Inquiry
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