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AGA


Official Full Name
aspartylglucosaminidase
Organism
Homo sapiens
Gene ID
175
Background
This gene encodes a member of the N-terminal nucleophile (Ntn) hydrolase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta chains that comprise the mature enzyme. This enzyme is involved in the catabolism of N-linked oligosaccharides of glycoproteins. It cleaves asparagine from N-acetylglucosamines as one of the final steps in the lysosomal breakdown of glycoproteins. Mutations in this gene are associated with the lysosomal storage disease aspartylglycosaminuria that results in progressive neurodegeneration. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is subject to proteolytic processing. [provided by RefSeq, Nov 2015]
Synonyms
GA; AGU; ASRG

Cat.No. Product Name Price
SHW000527 shRNA set against Chicken AGA (NM_001006445) Inquiry
SHG031663 shRNA set against Rat Aga(NM_001031641.1) Inquiry
SHH233094 shRNA set against Human AGA (NM_000027.3) Inquiry
SHH233098 shRNA set against Mouse AGA (NM_001005847.2) Inquiry
SHH233102 shRNA set against Rat AGA (NM_001031641.1) Inquiry
SHW012013 shRNA set against Danio rerio AGA (NM_001110281) Inquiry
Cat.No. Product Name Price
CDFH000452 Human AGA cDNA Clone(NM_001171988.1) Inquiry
CDFR004177 Rat Aga cDNA Clone(NM_001031641.1) Inquiry
MiUTR1R-00168 AGA miRNA 3'UTR clone Inquiry
MiUTR3H-12796 AGA miRNA 3'UTR clone Inquiry
SKO0293 AGA Validated sgRNA vector Inquiry
CDCB159761 Human AGA ORF clone (BC012392) Inquiry
CDCB162002 Chicken AGA ORF Clone (NM_001006445) Inquiry
CDCB173488 Danio rerio AGA ORF Clone (NM_001110281) Inquiry
CDCB194248 Rabbit AGA ORF clone (XM_002709483.2) Inquiry
CDCH015162 Mouse AGA ORF clone(NM_001005847.2) Inquiry
CDCR025434 Human AGA ORF clone (NM_001171988.1) Inquiry
CDCR025438 Mouse Aga ORF clone (NM_001205054.1) Inquiry
CDCR371203 Rat Aga ORF Clone(NM_001031641.1) Inquiry
CDCS405363 Human AGA ORF Clone (BC012392) Inquiry
Cat.No. Product Name Price
CC-88 AGA Easy KO Kit Inquiry
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