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ABCB8

Official Full Name
ATP binding cassette subfamily B member 8
Organism
Homo sapiens
GeneID
11194
Background
This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Synonyms
MABC1; M-ABC1; MITOSUR; EST328128;

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