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Rat Grm4-FLAG Stable Cell Line-HEK293T

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Cat.No.
CSC-RG0305
Background
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. The metabotropic glutamate receptors, which are G protein-coupled receptors, have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms and pharmacologic properties. Group II and group III receptors are linked to the inhibition of the cyclic AMP cascade, but differ in their agonist selectivity. Group III agonists include L-2-amino-4-phosphonobutyrate (LAP4) and L-serine-O-phosphate.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293T
Ship
Dry ice
Gene Information
Official Symbol
Grm4
Synonyms
GRM4; glutamate receptor, metabotropic 4; metabotropic glutamate receptor 4; mGluR4;
Gene ID
Pathway
GPCRs, Class C Metabotropic glutamate, pheromone, organism-specific biosystem; Glutamatergic synapse, organism-specific biosystem; Glutamatergic synapse, conserved biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem; Taste transduction, organism-specific biosystem; Taste transduction, conserved biosystem;
Function
G-protein coupled receptor activity; receptor activity; signal transducer activity;

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