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Mouse Mtnr1b-FLAG Stable Cell Line-HEK293T

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Cat.No.
CSC-RG0300
Background
MT2 receptor, also known as MTNR1B (Melatonin receptor type 1B), is a high affinity receptor for melatonin. It is known to mediate the reproductive and circadian actions of melatonin and is considered as a novel therapeutic target for the development of subtype-selective analogs for the treatment of circadian sleep and mood-related disorders. MT2 receptor is also likely to mediate the interfering with the apoptotic pathway activated by heat shock in HL-60 cells.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293T
Ship
Dry ice
Gene Information
Official Symbol
Mtnr1b
Synonyms
MTNR1B; melatonin receptor 1B; melatonin receptor type 1B; mel1b receptor; MT2 melatonin receptor; Mel-1b melatonin receptor; Mt2; Mel1b; Mel-1B-R; MGC129286; MGC129287;
Gene ID
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Other, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
G-protein coupled receptor activity; melatonin receptor activity; receptor activity; signal transducer activity;

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