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Mouse Ccr9-FLAG Stable Cell Line-HEK293T Gqi5

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Cat.No.
CSC-RG0214
Background
CCR9 (C-C chemokine receptor type 9) is a thymus-specific receptor for chemokine CCL25 (SCYA25 or TECK). It is an alternative co-receptor with CD4 for HIV-1 infection. Activation of the receptor may lead to potent cFLIP(L)-independent resistance to cycloheximide-induced apoptosis and modest resistance to Fas-mediated apoptosis possibly via activation of multiple signaling components involving Akt and glycogen synthase kinase 3beta. Thus, dissection of signaling components involved in the CCR9-mediated antiapoptosis could be a framework for cell survival mechanisms and may provide options for therapeutic interventions.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293T Gqi5
Ship
Dry ice
Gene Information
Official Symbol
Ccr9
Synonyms
CCR9; chemokine (C-C motif) receptor 9; C-C chemokine receptor type 9; CCR-9; CC-CKR-9; C-C CKR-9; chemokine C-C receptor 10; Cmkbr10; GPR-9-6; A130091K22Rik;
Gene ID
Pathway
Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; G alpha (i) signalling events, organism-specific biosystem;
Function
C-C chemokine receptor activity; G-protein coupled receptor activity; chemokine receptor activity; protein binding; receptor activity; signal transducer activity;

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