Tel: 1-631-626-9181 (USA)   44-207-097-1828 (Europe)

Human XCR1/Apoaequorin Stable Cell Line-CHO

See other products for XCR1
Cat.No.
CSC-RG1269
Background
The migration of leukocytes from the bloodstream to sites of inflammation is a dynamic factor involving adhesion molecules and chemotactic factors. Chemokines play a role in the trafficking of leukocytes by inducing cellular motility and activating adhesion molecules within the immune system. Lymphotactin (also known as XCL1 and SCM-1) is a unique chemokine that retains only two of the four cysteine residues found in the CC, CXC and CX3C families of chemokines. A Gi-coupled receptor, XCR1, binds to lymphotactin and mediates its chemotactic effects. Chemokines promote accumulation of activated mononuclear cells (MNCs) in inflamed joints in rheumatoid arthritis (RA) and lymphotacin is highly expressed in synovial fluid of RA patients. In situ hybridization studies indicate that XCR1 expression was detected in both the infiltrated MNCs and the synoviocytes from synovial specimens taken from RA patients.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
XCR1
Synonyms
XCR1; chemokine (C motif) receptor 1; CCXCR1, chemokine (C motif) XC receptor 1 , GPR5; chemokine XC receptor 1; lymphotactin receptor; XC chemokine receptor 1; G protein-coupled receptor 5; G-protein coupled receptor 5; chemokine (C motif) XC receptor 1; GPR5; CCXCR1;
Gene ID
MIM
UniProt ID
P46094
Chromosome Location
3p21.3-p21.1
Pathway
Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; G alpha (q) signalling events, organism-specific biosystem;
Function
G-protein coupled receptor activity; chemokine receptor activity; receptor activity; signal transducer activity;

Quick Inquiry

Please input "biogene" as verification code.

XCR1 Related Products

Transfected Stable Cell Lines

By Gene symbol(8)
+Expand
By Species(8)
+Expand

Clones

By Gene symbol(19)
+Expand
By Species(19)
+Expand
By MicroRNA Accession No.(2)
+Expand
By Selection(3)
+Expand

Contact Us

USA

Europe

CBpromise   

Our promise to you:
Guaranteed product quality, expert customer support.

24x7 CUSTOMER SERVICE
CONTACT US TO ORDER