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Human UTS2R/beta-Arrestin Stable Cell Line-CHO

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Cat.No.
CSC-RG1611
Background
The urotensin 2 receptor (UT or GPR14) is high affinity receptor for urotensin-2 and urotensin-2B. In human, Urotensin II is the most potent vasoconstrictor known, possibly contributing to several human cardiovascular diseases. Both UT receptor and urotensin II are widely expressed in many other tissues, implicating urotensin II in the pathogenesis of a variety of disease processes ranging from hypertension to hepatic cirrhosis and UT antagonists for the possibility of a new range of therapeutic drugs.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
UTS2R
Synonyms
UTS2R; urotensin 2 receptor; G protein coupled receptor 14 , GPR14; urotensin-2 receptor; UR-II-R; urotensin II receptor; G protein-coupled receptor 14; G-protein coupled receptor 14; UTR; UTR2; GPR14; UR-2-R;
Gene ID
MIM
UniProt ID
Q9UKP6
Chromosome Location
17q25.3
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Other, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
G-protein coupled receptor activity; receptor activity; signal transducer activity; urotensin II receptor activity;

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