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Human TBXA2R-FLAG Stable Cell Line-HEK293T

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Cat.No.
CSC-RG0369
Background
The human TP (thromboxane A2) receptor is a very potent stimulator of platelet aggregation and a constrictor of vascular and respiratory smooth muscles. It has been shown to be a mediator in diseases such as myocardial infarction, stroke and bronchial asthma. TP receptors can be found on platelets, as well as macrophages, monocytes, vascular endothelial cells, and smooth muscle cells. TP receptor antagonists may also play a role in the treatment of atherothrombosis and stroke prevention.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293T
Ship
Dry ice
Gene Information
Official Symbol
TBXA2R
Synonyms
TBXA2R; thromboxane A2 receptor; prostanoid TP receptor; TXA2-R; BDPLT13;
Gene ID
MIM
UniProt ID
P21731
Chromosome Location
19p13.3
Pathway
Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Eicosanoid ligand-binding receptors, organism-specific biosystem; G alpha (12/13) signalling events, organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem;
Function
G-protein coupled receptor activity; guanyl-nucleotide exchange factor activity; protein binding; receptor activity; signal transducer activity; thromboxane A2 receptor activity;

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