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Human TACR1/beta-Arrestin Stable Cell Line-CHO

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Cat.No.
CSC-RG1604
Background
Tachykinin receptor 1 (TACR1) also known as neurokinin 1 receptor (NK1R) or substance P receptor (SPR) belongs to a family of proteins characterized by the interaction with G proteins. TACR1 is localized both in the central nervous system (CNS) and peripheral tissues. Tachykinin receptor 1 presents great affinity for Substance P agonist. This receptor is an interesting drug target in the studies about analgesics and antidepressants.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
TACR1
Synonyms
TACR1; tachykinin receptor 1; TAC1R; substance-P receptor; NK1R; NKIR; SPR; NK-1R; NK-1 receptor; tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor);
Gene ID
MIM
UniProt ID
P25103
Chromosome Location
2p13.1-p12
Pathway
Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; Measles, organism-specific biosystem;
Function
G-protein coupled receptor activity; protein binding; receptor activity; signal transducer activity; substance P receptor activity; tachykinin receptor activity;

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