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Human SSTR2/Apoaequorin Stable Cell Line-CHO

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Cat.No.
CSC-RG1334
Background
Somatostatin receptors are activated by somatostatin secreted from nerve and endocrine cells. The Somatostatin Receptors (SSTRs) are expressed in a tissue-specific manner and involved in the regulation of secretion of insulin, glucagon and growth hormone as well as cell growth induced by neuronal excitation in both the central and peripheral nervous systems. Aberrent expression of somatostatin receptors is known in a large number of human tumours. SSTR2 is expressed in highest levels in the stomach, jejunum, cerebrum, thyroid and kidney. Its gene expression is lost in 90% of human pancreatic adenocarcinomas while SSTR2 expression in neuroblastoma correlates positively to overall and event-free survival. Expression of SSTR-2 and SSTR-5 may be important in the growth inhibitory effect of somatostatin in human pancreatic cancer.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
SSTR2
Synonyms
SSTR2; somatostatin receptor 2; SRIF-1; SS2R; somatostatin receptor type 2
Gene ID
MIM
UniProt ID
P30874
Chromosome Location
17q24
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
PDZ domain binding; protein binding; somatostatin receptor activity
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AD15575Z
>1x 10^9 vp/ml
1 x 0.2 ml
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Email: info@creative-biogene.com
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CONTACT CREATIVE BIOGENE

45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-biogene.com

Europe
Tel: 44-207-097-1828

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