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Human SSTR1-FLAG Stable Cell Line-CHO-K1 Galpha16

See other products for SSTR1
Cat.No.
CSC-RG0396
Background
Somatostatin receptors are activated by somatostatin secreted from nerve and endocrine cells. The Somatostatin Receptors (SSTRs) are expressed in a tissue-specific manner and involved in the regulation of secretion of insulin, glucagon and growth hormone as well as cell growth induced by neuronal excitation in both the central and peripheral nervous systems. Aberrent expression of somatostatin receptors is known in a large number of human tumours. The human medullary thyroid carcinoma cell line TT expresses all SSTR subtypes. SSTR1 has been reported at highest levels in the jejunum and stomach. In addition, this receptor is expressed in adrenal, brain, liver, lung, eye, and pancreas. ESTs from SSTR1 have been isolated from normal placenta and colon cancer libraries. Normal T-cells expressed SSTR1 and SSTR5 while T-cell leukaemia lines do not. Selective activation of SSTR1 inhibits hormone secretion and cell viability in GH- secreting and PRL-secreting adenomas in vitro.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1 Galpha16
Ship
Dry ice
Gene Information
Official Symbol
SSTR1
Synonyms
SSTR1; somatostatin receptor 1; somatostatin receptor type 1; G-protein coupled receptor; SS1R; SS1-R; SRIF-2; SS-1-R;
Gene ID
MIM
UniProt ID
P30872
Chromosome Location
14q13
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
G-protein coupled receptor activity; receptor activity; signal transducer activity; somatostatin receptor activity;
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AD15574Z
>1x 10^9 vp/ml
1 x 0.2 ml
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CONTACT CREATIVE BIOGENE

45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-biogene.com

Europe
Tel: 44-207-097-1828

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