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Human S1PR5-FLAG Stable Cell Line-CHO-K1 Galphaqi5

Cat.No.
CSC-RG0293
Abbr
CHO-K1 Galphaqi5-HuS1PR5-FLAG
Alias
S1PR5,EDG8,Edg 8,S1P5,Edg-8,SPPR-1,SPPR-2
Growth Properties
Adherent
Host Cell
CHO-K1 Galphaqi5
Morphology
Epithelial-like
Shipping
Dry ice
Species
Human
Background
The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retractions. S1P and the structurally related LPA signal cells through a set of G-protein-coupled receptors known as EDG receptors. S1P5 or EDG8 is a 400-amino acid 7 transmembrane protein that shares 42-49% amino acid identity with the human S1P receptors EDG1, EDG3, and EDG5. Northern blot analysis has shown widespread expression of EDG8 in rat tissues, with strongest expression in spleen and white matter tracts of the brain.

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