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Human S1PR4/Apoaequorin Stable Cell Line-CHO

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Cat.No.
CSC-RG1298
Background
Sphingosine 1-phosphate (S1P) is a biologically active lysophospholipid that transmits signals through a family of five G-protein-coupled receptors to regulate cell proliferation, migration, cytoskeletal organization, and differentiation. S1P4 receptor was reported to couple to multiple subsets of heterotrimeric G proteins (including Gi/o, and G12/13 , and possibly Gs). Unlike other S1P receptors, S1P4 expression is restricted in human and mouse to lymph node, spleen, lung, and thymus. This expression pattern suggests potential roles of S1P4 in the immune system.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
S1PR4
Synonyms
S1PR4; sphingosine-1-phosphate receptor 4; EDG6, endothelial differentiation, G protein coupled receptor 6 , endothelial differentiation, lysophosphatidic acid G protein coupled receptor, 6; sphingosine 1-phosphate receptor 4; S1P receptor 4; S1P receptor Edg-6; sphingosine 1-phosphate receptor Edg-6; endothelial differentiation G-protein coupled receptor 6; endothelial differentiation, G protein coupled receptor 6; endothelial differentiation, G-protein-coupled receptor 6; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 6; EDG6; LPC1; S1P4; SLP4;
Gene ID
MIM
UniProt ID
O95977
Chromosome Location
19p13.3
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; Lysosphingolipid and LPA receptors, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
G-protein coupled receptor activity; lipid binding; receptor activity; signal transducer activity; sphingosine-1-phosphate receptor activity;

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