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Human S1PR3/beta-Arrestin Stable Cell Line-HEK293

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Cat.No.
CSC-RG1482
Background
S1P3 (sphingosine 1-phosphate receptor 3) or EDG3 (endothelial differentiation G-protein coupled receptor 3) is a receptor for the lysosphingolipid sphingosine 1-phosphate, a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. EDG receptors mediate proangiogenic activities, such as endothelial cell proliferation, chemotaxis, and vessel morphogenesis. S1P3, along with S1P1, is required for directing the organization of endothelial cells into capillary networks.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293
Ship
Dry ice
Gene Information
Official Symbol
S1PR3
Synonyms
S1PR3; sphingosine-1-phosphate receptor 3; EDG3, endothelial differentiation, sphingolipid G protein coupled receptor, 3; sphingosine 1-phosphate receptor 3; EDG 3; sphingosine 1 phosphate receptor 3; S1P receptor 3; S1P receptor EDG3; S1P receptor Edg-3; sphingosine 1-phosphate receptor Edg-3; endothelial differentiation G-protein coupled receptor 3; G protein-coupled receptor, endothelial differentiation gene-3; endothelial differentiation, sphingolipid G-protein-coupled receptor, 3; EDG3; LPB3; S1P3; EDG-3; FLJ37523; FLJ93220; MGC71696;
Gene ID
MIM
UniProt ID
Q99500
Chromosome Location
9q22.1-q22.2
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; Lysosphingolipid and LPA receptors, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
G-protein coupled receptor activity; lipid binding; receptor activity; signal transducer activity; sphingosine-1-phosphate receptor activity;

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