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Human PTH2R/Gs Stable Cell Line-CHO

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Cat.No.
CSC-RG0482
Background
The parathyroid hormone (PTH) receptor type 2 (PTHR2) is a receptor for PTH and tuberoinfundibular peptide TIP39. Unlike the PTH1 receptor, the PTH2 receptor has extreme low affinity for PTH-related peptide PTHrP. PTH2 receptor expression is high in the CNS, where it is concentrated in limbic, hypothalamic, and sensory areas, especially hypothalamic periventricular neurons, nerve terminals in the median eminence, superficial layers of the spinal cord dorsal horn, and the caudal part of the sensory trigeminal nucleus. Peripheral expression in pancreatic islet somatostatin cells is most dramatic. PTHR2 may be functionally involved in pituitary and pancreatic hormone release and pain perception.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
PTH2R
Synonyms
PTH2R; parathyroid hormone 2 receptor; parathyroid hormone receptor 2 , PTHR2; PTH2 receptor; parathyroid hormone receptor 2; PTHR2;
Gene ID
MIM
UniProt ID
P49190
Chromosome Location
2q33
Pathway
Class B/2 (Secretin family receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class B Secretin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
parathyroid hormone receptor activity; receptor activity; signal transducer activity;

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