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Human PTGFR-FLAG Stable Cell Line-HEK293T

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Cat.No.
CSC-RG0367
Background
Prostaglandin F (2-alpha) is involved in a number of physiologic processes. It serves as a potent luteolytic agent in many species, has been implicated as a modulator of intraocular pressure, smooth muscle contraction in the uterus and elsewhere. Its effects on cells are mediated through specific interaction with the prostaglandin F receptor (FP or PTGFR). Knockout mice lacking the FP receptor are unable to deliver normal fetuses at term due to a lack of response to oxytocin. The mice also failed to show the decline in serum progesterone expected to precede parturition.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293T
Ship
Dry ice
Gene Information
Official Symbol
PTGFR
Synonyms
PTGFR; FP; prostaglandin F receptor (FP); RP5-944H6.1; PGF receptor; PGF2 alpha receptor; PGF2-alpha receptor; prostaglandin F2 alpha receptor; prostaglandin F2-alpha receptor; prostaglandin receptor (2-alpha); prostanoid FP receptor
Gene ID
MIM
UniProt ID
P43088
Chromosome Location
1p31.1
Pathway
Calcium signaling pathway; Class A/1 (Rhodopsin-like receptors); Eicosanoid ligand-binding receptors; GPCR downstream signaling; GPCR ligand binding; GPCRs, Class A Rhodopsin-like; Gastrin-CREB signalling pathway via PKC and MAPK
Function
prostaglandin F receptor activity

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