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Human PTGDR2 Stable Cell Line-CHO-K1/Gα15

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Cat.No.
CSC-RG1701
Background
This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.
Host Cell
CHO-K1/Gα15
Ship
Dry Ice
Antigen Gene Information
Official Symbol
PTGDR2
Synonyms
PTGDR2; prostaglandin D2 receptor 2; G protein coupled receptor 44 , GPR44; CD294; chemoattractant receptor homologous molecule expressed on T helper type 2 cells; CRTH2; DP2; G protein-coupled receptor 44; G-protein coupled receptor 44; putative G-protein coupled receptor 44; chemoattractant receptor-homologous molecule expressed on TH2 cells; DL1R; GPR44;
GeneID
MIM
UniProt ID
Q9Y5Y4
Chromosome Location
11q12-q13.3
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Eicosanoid ligand-binding receptors, organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Prostanoid ligand receptors, organism-specific biosystem;
Function
G-protein coupled receptor activity; N-formyl peptide receptor activity; prostaglandin D receptor activity; prostaglandin F receptor activity; prostaglandin J receptor activity; receptor activity; signal transducer activity;

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