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Human PTAFR-FLAG Stable Cell Line-HEK293T

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Cat.No.
CSC-RG0463
Background
The platelet-activating factor (PAF) receptor mediates a wide range of biological responses to PAF, a potent glycerophospholipid released from a variety of cell types such as stimulated basophils, platelets, polymorphonuclear neutrophils and macrophages. PAF is involved in a diverse array of biological activities related to inflammatory and immune responses as well as cardiovascular, respiratory and nervous system physiology. In humans, various diseases have been associated with PAF, such as allergic asthma, endotoxic shock, atherosclerosis and psoriasis.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293T
Ship
Dry ice
Gene Information
Official Symbol
PTAFR
Synonyms
PTAFR; PAFR; platelet-activating factor receptor; PAF-R
Gene ID
MIM
UniProt ID
P25105
Chromosome Location
1p35-p34.3
Pathway
Calcium signaling pathway; Class A/1 (Rhodopsin-like receptors); Cytokine Signaling in Immune system; G alpha (q) signalling events; GPCR downstream signaling; GPCR ligand binding; GPCRs, Class A Rhodopsin-like;
Function
G-protein coupled receptor activity; lipopolysaccharide binding; lipopolysaccharide receptor activity; phospholipid binding; platelet activating factor receptor activity

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