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Human PROKR2/Apoaequorin Stable Cell Line-CHO

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Cat.No.
CSC-RG1323
Background
Prokineticins, also known as endocrine gland vascular endothelial growth factors (EG-VEGF), are two approximately 10 kD secreted proteins originally described to mediate angiogenesis and gastrointestinal smooth muscle contraction. Subsequently, prokineticins have been found to mediate central nervous system functions including circadian rhythms and olfactory bulb development. Two Gq-coupled receptors, PK1 and PK2, mediate cellular responses to prokineticins. The phenotype of the PK2-null mouse indicates that PK2 promotes development of the olfactory bulb and several male and female reproductive organs.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
PROKR2
Synonyms
PROKR2; prokineticin receptor 2; G protein coupled receptor 73 like 1 , GPR73L1, KAL3, Kallmann syndrome 3 (autosomal dominant); dJ680N4.3; GPR73b; GPRg2; PKR2; PK-R2; G protein-coupled receptor 73-like 1; KAL3; GPR73L1;
Gene ID
MIM
UniProt ID
Q8NFJ6
Chromosome Location
20p12.3
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Other, organism-specific biosystem; Peptide ligand-binding receptors, organism-specific biosystem; Signal Transduction, organism-specific biosystem;
Function
G-protein coupled receptor activity; neuropeptide Y receptor activity; receptor activity; signal transducer activity;

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