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Human PPYR1-FLAG Stable Cell Line-CHO-K1 Galphaqi5

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Cat.No.
CSC-RG0333
Background
NPY4R (Y4) has been reported to be expressed at highest levels in brain, coronary artery and ileum, low levels in pancreas and kidney. It is also been detected in colon and small intestine and isolated from human colon and head/neck libraries. It is one of the receptors for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PP, PP (2-36) and [Ile-31, Gln-34] PP >[Pro-34] PYY >PYY and [Leu-31, Pro-34] NPY >NPY >PYY (3-36) and NPY (2-36) >PP (13-36) >PP (31-36) >NPY free acid. Ligand: Neuropeptide Y, Peptide YY.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1 Galphaqi5
Ship
Dry ice
Gene Information
Official Symbol
PPYR1
Synonyms
PPYR1; pancreatic polypeptide receptor 1; neuropeptide Y receptor type 4; NPY4R; PP1; Y4; NPY4-R; MGC116897;
Gene ID
MIM
UniProt ID
P50391
Chromosome Location
10q11.2
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
G-protein coupled receptor activity; pancreatic polypeptide receptor activity; peptide YY receptor activity; peptide binding; receptor activity; signal transducer activity;

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