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Human P2RY6-FLAG Stable Cell Line-1321N1

Cat.No.
CSC-RG0380
Abbr
1321N1-HuP2RY6-FLAG
Alias
P2RY6,P2Y6,MGC15335
Growth Properties
Adherent
Host Cell
1321N1
Morphology
Glial
Shipping
Dry ice
Species
Human
Background
The human P2Y6 receptor is a member of the G protein-coupled P2 receptor family that responds specifically to the extracellular nucleotide uridine diphosphate (UDP). The distribution of the P2Y6 receptor is widespread including heart, blood vessels and brain. P2Y6 receptors are significantly upregulated in T cells infiltrating regions of inflamed bowel and are involved in monocytic release of IL-8 in response to UDP or lipopolysaccharide (LPS). The immune effect of UDP/P2Y6 signaling on the production of proinflammatory cytokines has been shown to be selective and dependent on cell types.

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