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Human P2RY4/Galpha15 Stable Cell Line-1321N1

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Cat.No.
CSC-RG0726
Background
The P2Y GPCRs serve as receptors for extracellular nucleotides. The P2Y4 receptor is activated by UTP, and also by ATP in rodents, and couples to Gq to increase intracellular calcium. P2Y4 is expressed prominently in the intestinal epithelium, where it regulates intestinal chloride secretion. P2Y4 therefore is likely to be involved in infectious diarrhea caused by nucleotides released upon infection with enteropathogenic bacteria.
Growth Properties
Adherent
Morphology
Glial
Host Cell
1321N1
Ship
Dry ice
Gene Information
Official Symbol
P2RY4
Synonyms
P2RY4; pyrimidinergic receptor P2Y, G-protein coupled, 4; P2Y purinoceptor 4; NRU; P2P; P2Y4; UNR; uridine nucleotide receptor;
Gene ID
MIM
UniProt ID
P51582
Chromosome Location
Xq13
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
ATP binding; G-protein coupled purinergic nucleotide receptor activity; G-protein coupled receptor activity; UTP-activated nucleotide receptor activity; receptor activity; signal transducer activity; uridine nucleotide receptor activity;

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