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Human P2RY13-FLAG Stable Cell Line-1321N1

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Cat.No.
CSC-RG0375
Background
GPR86 or P2Y13 is a 333-amino acid 7 transmembrane protein that lacks a leader peptide but posseses a DRF motif. Northern blot and PCR analysis has shown GPR86 to be expressed highly in the spleen, with weaker expression in placenta, leukocytes, brain, placenta, lung, liver, spinal cord, thymus, small intestine, uterus, stomach, testis, fetal brain and adrenal glad and no expression in the pancreas, heart, kidney, skeletal muscle, ovary or fetal aorta. Communi et al determined that GPR86 shows a high affinity for ADP through pharmacologic charactization of GPR86-transfected human astrocytoma cells and CHO cells.
Growth Properties
Adherent
Morphology
Glial
Host Cell
1321N1
Ship
Dry ice
Gene Information
Official Symbol
P2RY13
Synonyms
P2RY13; purinergic receptor P2Y, G-protein coupled, 13; G protein coupled receptor 86 , GPR86, GPR94; P2Y purinoceptor 13; FKSG77; P2Y13; G protein-coupled receptor 86; G-protein coupled receptor 86; G-protein coupled receptor 94; GPCR1; GPR86; GPR94; SP174;
Gene ID
MIM
UniProt ID
Q9BPV8
Chromosome Location
3q24
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; GPCRs, Other, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem;
Function
G-protein coupled purinergic nucleotide receptor activity; G-protein coupled receptor activity; receptor activity; signal transducer activity;

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