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Human P2RY11/beta-Arrestin Stable Cell Line-CHO

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Cat.No.
CSC-RG1576
Background
P2Y purinoceptor 11 encodes P2Y11 (P2Y11) which is a receptor for ATP and ADP coupled to G-proteins that activate both phosphatidylinositol-calcium and adenylyl cyclase second messenger systems. P2Y11 receptor is unique amongst P2Y receptors with its coupling to the adenylyl cyclase pathway. Through this mechanism, released nucleotides can increase in P2Y11-containing cells. P2Y11 receptor has been reported to be involved in the granulocytic differentiation of promyelocytes and in the maturation of monocyte-derived dendritic cells.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
P2RY11
Synonyms
P2RY11; purinergic receptor P2Y, G-protein coupled, 11; P2Y purinoceptor 11; P2Y11; purinergic receptor P2Y11;
Gene ID
MIM
UniProt ID
Q96G91
Chromosome Location
19p13.2
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; GPCRs, Other, organism-specific biosystem;
Function
ATP-activated nucleotide receptor activity; G-protein coupled purinergic nucleotide receptor activity; G-protein coupled receptor activity; neurotransmitter receptor activity; receptor activity; signal transducer activity;

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