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Human P2RY11/Clytin Stable Cell Line-1321N1

See other products for P2RY11
Cat.No.
CSC-RG0721
Background
The P2Y GPCRs serve as receptors for extracellular nucleotides. P2Y11 is a relatively low affinity receptor for ATP present humans but not rodents. It is unique among P2Y receptors in increasing both cAMP and calcium levels. P2Y11 is expressed in immune cells, and it mediates dendritic cell maturation induced by ATP. In addition to ATP, NAD+ and NADP+ bind and activate P2Y11 in granulocytes. An alternate form of P2Y11, in which the second exon of P2Y11 undergoes intergenic splicing with exon 12 of the adjacent SSF1 gene to generate a chimeric protein, is widely expressed in human tissues.
Growth Properties
Adherent
Morphology
Glial
Host Cell
1321N1
Ship
Dry ice
Gene Information
Official Symbol
P2RY11
Synonyms
P2RY11; purinergic receptor P2Y, G-protein coupled, 11; P2Y purinoceptor 11; P2Y11; purinergic receptor P2Y11;
Gene ID
MIM
UniProt ID
Q96G91
Chromosome Location
19p13.2
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; GPCRs, Other, organism-specific biosystem;
Function
ATP-activated nucleotide receptor activity; G-protein coupled purinergic nucleotide receptor activity; G-protein coupled receptor activity; neurotransmitter receptor activity; receptor activity; signal transducer activity;
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