Tel: 1-631-626-9181 (USA)   44-207-097-1828 (Europe)
  Email:

Human P2RY1/beta-Arrestin Stable Cell Line-U2OS

Cat.No.
CSC-RG1571
Abbr
U2OS-HuP2RY1/beta-Arrestin
Alias
P2RY1,P2Y1
Growth Properties
Adherent
Host Cell
U2OS
Morphology
Epithelial
Shipping
Dry ice
Species
Human
Background
P2Y1 is a receptor for ATP and ADP. P2Y1 contributes to platelet shape change. A number of P2Y1 receptor-specific antagonists, such as, MRS-2179, A3P5PS, A3P5P and A2P5P have been discovered. They inhibit calcium ion mobilization and shape change in platelets. P2Y1-deficient mice and mice treated with the P2Y1 antagonist MRS2179 displayed significantly less arterial thrombosis than their respective controls. Combination of P2Y1 deficiency with P2Y12 inhibition led to a significant additive effect.

Quick Inquiry

   Please input "biogene" as verification code.