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Human OPRM1/Galpha15 Stable Cell Line-Chem-5

See other products for OPRM1
Cat.No.
CSC-RG0711
Background
Opiates derived from the opium poppy, Papaver somniferum, have been used in for millenia for their anti-diarrheal, analgesic and euphoric properties. More recently, endogenous peptides, enkephalins, dynorphins, and endorphins, were found to bind to the same sites as opiate alkaloids. The receptors for the classical opioids are three related GPCRs, mu, delta, and kappa, that activate Gi/o to reduce intracellular cAMP levels. Most clinically used opioids function by activation of the mu opioid receptor.
Growth Properties
Adherent
Host Cell
Chem-5
Ship
Dry ice
Gene Information
Official Symbol
OPRM1
Synonyms
OPRM1; opioid receptor, mu 1; mu-type opioid receptor; MOR1; MOP; hMOP; M-OR-1; mu opiate receptor; mu opioid receptor hMOR-1a; mu opioid receptor splice variant hMOR-1S; mu opioid receptor splice variant hMOR-1Z; mu opioid receptor splice variant hMOR-1b; mu opioid receptor splice variant hMOR-1Y2; mu opioid receptor splice variant hMOR-1Y3; MOR; LMOR; OPRM; KIAA0403;
Gene ID
MIM
UniProt ID
P35372
Chromosome Location
6q24-q25
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; G-protein activation, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; IL4-mediated signaling events, organism-specific biosystem;
Function
G-protein alpha-subunit binding; G-protein coupled receptor activity; beta-endorphin receptor activity; morphine receptor activity; protein binding; receptor activity; signal transducer activity;
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