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Human OPRL1/Gi Stable Cell Line-CHO

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Cat.No.
CSC-RG0539
Background
Opioid receptors are widely distributed in brain, spinal cord and peripheral sensory and autonomic nerves. They are activated physiologically by the products of endogenous opioid peptide genes such as proenkephalin, podynorphin, pro-opiomelancortin and pronociceptin. Four opioid receptor subtypes have been identified including μ, delta, kappa, and ORL1. All of these subtypes are coupled to cAMP modulation via Gi/o but each subtype has a distinct pharmacological profile.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
OPRL1
Synonyms
OPRL1; opiate receptor-like 1; nociceptin receptor; kappa3 related opioid receptor; KOR 3; LC132 receptor like; NOCIR; OOR; ORL1; orphanin FQ receptor; kappa-type 3 opioid receptor; kappa3-related opioid receptor; KOR-3; MGC34578;
Gene ID
MIM
UniProt ID
P41146
Chromosome Location
20q13.33
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
G-protein coupled receptor activity; nociceptin receptor activity; receptor activity; signal transducer activity;

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