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Human OPRL1/Galpha15 Stable Cell Line-Chem-1

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Cat.No.
CSC-RG0712
Background
The protein encoded by this gene is a G protein-coupled receptor whose expression can be induced by phytohemagglutinin. The encoded integral membrane protein is a receptor for the 17 aa neuropeptide nociceptin/orphanin FQ. This gene may be involved in the regulation of numerous brain activities, particularly instinctive and emotional behaviors. A promoter for this gene also functions as a promoter for another gene, regulator of G-protein signalling 19 (RGS19), located on the opposite strand. Three transcript variants encoding the same protein have been found for this gene.
Growth Properties
Adherent
Host Cell
Chem-1
Ship
Dry ice
Gene Information
Official Symbol
OPRL1
Synonyms
OPRL1; opiate receptor-like 1; nociceptin receptor; kappa3 related opioid receptor; KOR 3; LC132 receptor like; NOCIR; OOR; ORL1; orphanin FQ receptor; kappa-type 3 opioid receptor; kappa3-related opioid receptor; KOR-3; MGC34578;
Gene ID
MIM
UniProt ID
P41146
Chromosome Location
20q13.33
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
G-protein coupled receptor activity; nociceptin receptor activity; receptor activity; signal transducer activity;

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