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Human OPRK1/beta-Arrestin Stable Cell Line-U2OS

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Cat.No.
CSC-RG1564
Background
kappa-opioid receptor is one of five related receptors that bind opium-like compounds in the brain and are responsible for mediating the effects of these compounds. These effects include altering the perception of pain, consciousness, motor control, and mood. Opioid receptors mediate the analgesic action and addictive properties of opioid drugs. The kappa-opioid receptor may provide a natural addiction control mechanism, and consequently selective agonists of this receptor may have therapeutic potential in the treatment of addiction.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
U2OS
Ship
Dry ice
Gene Information
Official Symbol
OPRK1
Synonyms
OPRK1; opioid receptor, kappa 1; kappa-type opioid receptor; KOR; KOR-1; K-OR-1; kappa opioid receptor; Opiate receptor, kappa-1; OPRK;
Gene ID
MIM
UniProt ID
P41145
Chromosome Location
8q11.2
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
G-protein coupled receptor activity; dynorphin receptor activity; protein binding; receptor activity; signal transducer activity;

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