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Human OPRK1-FLAG Stable Cell Line-HEK293T

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Cat.No.
CSC-RG0343
Background
kappa Opioid Receptor (KOR) is a receptor for dynorphins. KOR inhibits neurotransmitter release by reducing calcium currents and increasing potassium conductance and may play a role in arousal and regulation of autonomic and neuroendocrine functions. Some studies suggest that stimulation of KOR improves memory dysfunctions resulting from the blockade of muscarinic M1 receptors. In addition, KOR agonists attenuate several behavioral responses induced by drugs of abuse, raising the possibility that KOR agonists may be useful for the treatment of dependence on drugs of abuse.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293T
Ship
Dry ice
Gene Information
Official Symbol
OPRK1
Synonyms
OPRK1; opioid receptor, kappa 1; kappa-type opioid receptor; KOR; KOR-1; K-OR-1; kappa opioid receptor; Opiate receptor, kappa-1; OPRK;
Gene ID
MIM
UniProt ID
P41145
Chromosome Location
8q11.2
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
G-protein coupled receptor activity; dynorphin receptor activity; protein binding; receptor activity; signal transducer activity;

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