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Human O3FAR1/beta-Arrestin Stable Cell Line-CHO

Cat.No.
CSC-RG1520
Abbr
CHO-HuO3FAR1/beta-Arrestin
Alias
O3FAR1,GPR120,GPR129,PGR4,GT01,BMIQ10,MGC119984,DKFZp686F0824
Growth Properties
Adherent
Host Cell
CHO-K1
Morphology
Epithelial-like
Shipping
Dry ice
Species
Human
Background
GPR120 is a G protein-coupled receptor for the long-chain free fatty acids. GPR120 mediated calcium mobilization, Erk1/Erk2 activation and GLP1 secretion. Unsaturated long-chain FFAs had a dose-dependent stimulatory effect, and -linolenic acid was the most potent. GPR120 and GLP1 colocalized in human colonic intraepithelial neuroendocrine cells, and GPR120 may mediate dietary FFAstimulated GLP1 secretion.

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