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Human O3FAR1/beta-Arrestin Stable Cell Line-CHO

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Cat.No.
CSC-RG1520
Background
GPR120 is a G protein-coupled receptor for the long-chain free fatty acids. GPR120 mediated calcium mobilization, Erk1/Erk2 activation and GLP1 secretion. Unsaturated long-chain FFAs had a dose-dependent stimulatory effect, and -linolenic acid was the most potent. GPR120 and GLP1 colocalized in human colonic intraepithelial neuroendocrine cells, and GPR120 may mediate dietary FFAstimulated GLP1 secretion.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
O3FAR1
Synonyms
O3FAR1; omega-3 fatty acid receptor 1; G protein coupled receptor 120 , G protein coupled receptor 129 , GPR120, GPR129; PGR4; G protein-coupled receptor 120; G protein-coupled receptor 129; G-protein coupled receptor 120; G-protein coupled receptor 129; G protein-coupled receptor PGR4; G-protein coupled receptor GT01; G-protein coupled receptor PGR4; G-protein-coupled receptor GT01; GT01; BMIQ10; GPR120; GPR129; MGC119984; DKFZp686F0824;
Gene ID
MIM
UniProt ID
Q5NUL3
Chromosome Location
10q23.33
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Free fatty acid receptors, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; Incretin Synthesis, Secretion, and Inactivation, organism-specific biosystem; Integration of energy metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Regulation of Insulin Secretion, organism-specific biosystem;
Function
fatty acid binding; receptor activity; signal transducer activity; taste receptor activity;

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