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Human O3FAR1-FLAG Stable Cell Line-HEK293T Galphaqi5

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Cat.No.
CSC-RG0433
Background
GPR120 is a G protein-coupled receptor for the long-chain free fatty acids. GPR120 mediated calcium mobilization, Erk1/Erk2 activation and GLP1 secretion. Unsaturated long-chain FFAs had a dose-dependent stimulatory effect, and -linolenic acid was the most potent. GPR120 and GLP1 colocalized in human colonic intraepithelial neuroendocrine cells, and GPR120 may mediate dietary FFAstimulated GLP1 secretion.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293T Galphaqi5
Ship
Dry ice
Gene Information
Official Symbol
O3FAR1
Synonyms
O3FAR1; omega-3 fatty acid receptor 1; G protein coupled receptor 120 , G protein coupled receptor 129 , GPR120, GPR129; PGR4; G protein-coupled receptor 120; G protein-coupled receptor 129; G-protein coupled receptor 120; G-protein coupled receptor 129; G protein-coupled receptor PGR4; G-protein coupled receptor GT01; G-protein coupled receptor PGR4; G-protein-coupled receptor GT01; GT01; BMIQ10; GPR120; GPR129; MGC119984; DKFZp686F0824;
Gene ID
MIM
UniProt ID
Q5NUL3
Chromosome Location
10q23.33
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Free fatty acid receptors, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; Incretin Synthesis, Secretion, and Inactivation, organism-specific biosystem; Integration of energy metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Regulation of Insulin Secretion, organism-specific biosystem;
Function
fatty acid binding; receptor activity; signal transducer activity; taste receptor activity;
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CONTACT CREATIVE BIOGENE

45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-biogene.com

Europe
Tel: 44-207-097-1828

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