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Human O3FAR1/Apoaequorin Stable Cell Line-CHO

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Cat.No.
CSC-RG1286
Background
It has been demonstrated that Omega-3 fatty acid administration to obese mice inhibited inflammation and enhanced insulin sensitivity, but these effects were absent in GPR120 knockout mice. GPR120 agonists may prove to be useful in suppression of chronic inflammation seen in obesity, which could reduce insulin resistance and help restore glucose control. A recent review suggests that the effects of marine n-3 fatty acids on inflammatory markers studied in healthy subjects, those at high risk for developing Cardiovascular Disease, and those with diagnosed Cardiovascular Disease are as yet not conclusive.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
O3FAR1
Synonyms
O3FAR1; omega-3 fatty acid receptor 1; G protein coupled receptor 120 , G protein coupled receptor 129 , GPR120, GPR129; PGR4; G protein-coupled receptor 120; G protein-coupled receptor 129; G-protein coupled receptor 120; G-protein coupled receptor 129; G protein-coupled receptor PGR4; G-protein coupled receptor GT01; G-protein coupled receptor PGR4; G-protein-coupled receptor GT01; GT01; BMIQ10; GPR120; GPR129; MGC119984; DKFZp686F0824;
Gene ID
MIM
UniProt ID
Q5NUL3
Chromosome Location
10q23.33
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Free fatty acid receptors, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; Incretin Synthesis, Secretion, and Inactivation, organism-specific biosystem; Integration of energy metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Regulation of Insulin Secretion, organism-specific biosystem;
Function
fatty acid binding; receptor activity; signal transducer activity; taste receptor activity;

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