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Human NPY2R/Apoaequorin Stable Cell Line

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Cat.No.
CSC-RG1313
Background
The NPY family consists of three 36-amino acid peptides, neuropeptide Y (NPY), peptide YY (PYY) and pancreatic polypeptide (PP), which bind to the NPY receptor family of G protein-coupled receptors. Five NPY receptors, Y1, Y2, Y4, Y5 and Y6, have been defined at the molecular level, and each signals primarily through Gi/o. Binding of NPY family peptides to NPY receptors mediates a variety of physiological effects, including promotion of food intake, decreased anxiety, inhibition of neurotransmitter and hormone release, vasoconstriction, and gut motility. Y2 is primarily expressed in the CNS, and it mediates presynaptic inhibition of neurotransmitter release.
Ship
Dry ice
Gene Information
Official Symbol
NPY2R
Synonyms
NPY2R; neuropeptide Y receptor Y2; neuropeptide Y receptor type 2; Y2 receptor; NPY-Y2 receptor; NPY2-R;
Gene ID
MIM
UniProt ID
P49146
Chromosome Location
4q31
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
G-protein coupled receptor activity; calcium channel regulator activity; neuropeptide Y receptor activity; peptide YY receptor activity; receptor activity; signal transducer activity;

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