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Human NPSR1-FLAG Stable Cell Line-HEK293T

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Cat.No.
CSC-RG0325
Background
Neuropeptide S (NPS) receptor 1 is also known as GPR154 or G protein-coupled receptor for asthma susceptibility (GPRA). NPS receptor is widely expressed in the brain, with highest levels found in hypothalamus, amygdala, endopiriform nucleus, cortex, subiculum and nuclei of the thalamic midline. Central administration of NPS promotes behavioral arousal and suppresses all stages of sleep in rodents. Furthermore, NPS was found to produce anxiolytic-like effects in a battery of four different tests that measure behavioral responses of rodents to novelty or stress.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293T
Ship
Dry ice
Gene Information
Official Symbol
NPSR1
Synonyms
NPSR1; neuropeptide S receptor 1; G protein coupled receptor 154 , GPR154; neuropeptide S receptor; GPRA; PGR14; G protein-coupled receptor 154; G-protein coupled receptor 154; G-protein coupled receptor PGR14; vasopressin receptor-related receptor 1; G protein-coupled receptor for asthma susceptibility; G-protein coupled receptor for asthma susceptibility; NPSR; VRR1; ASRT2; GPR154;
Gene ID
MIM
UniProt ID
Q6W5P4
Chromosome Location
7p14.3
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; Peptide ligand-binding receptors, organism-specific biosystem; Signal Transduction, organism-specific biosystem;
Function
G-protein coupled receptor activity; receptor activity; signal transducer activity; vasopressin receptor activity;

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