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Human NPBWR1 Stable Cell Line-HEK293T Galphaqi5

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Cat.No.
CSC-RG0328
Background
Neuropeptide B/neuropeptide W receptor 1 (NPBW1 or GPR7) is a receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Targeted disruption of NPBW1 in mice has confirmed that this receptor plays a role in maintaining long-term energy homeostasis. NPBW1 lacking male mice show moderately severe, late-onset obesity that is a result of both hyperphagia and decreased energy expenditure with reduced locomotor activity.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293T Galphaqi5
Ship
Dry ice
Gene Information
Official Symbol
NPBWR1
Synonyms
NPBWR1; neuropeptides B/W receptor 1; G protein coupled receptor 7 , GPR7; neuropeptides B/W receptor type 1; neuropeptide B/W receptor 1; G protein-coupled receptor 7; G-protein coupled receptor 7; opioid-somatostatin-like receptor 7; GPR7; MGC129755;
Gene ID
MIM
UniProt ID
P48145
Chromosome Location
8p22-q21.13
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
G-protein coupled receptor activity; opioid receptor activity; protein binding; receptor activity; signal transducer activity;

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