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Human NPBWR1/Gi Stable Cell Line-CHO

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Cat.No.
CSC-RG0523
Background
Relevance GPR7 interacts specifically with a number of opioid ligands. It is a receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals, and has a higher affinity for neuropeptide B. It has been reported in brain, mainly cerebellum and frontal cortex, and in the pituitary (O"Dowd et al., 1995). The mouse ortholog of GPR7 was shown by in situ hybridization to be expressed in discrete nuclei of brain, namely suprachiasmatic, arcuate, and ventromedial nuclei of hypothalamus.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
NPBWR1
Synonyms
NPBWR1; neuropeptides B/W receptor 1; G protein coupled receptor 7 , GPR7; neuropeptides B/W receptor type 1; neuropeptide B/W receptor 1; G protein-coupled receptor 7; G-protein coupled receptor 7; opioid-somatostatin-like receptor 7; GPR7; MGC129755;
Gene ID
MIM
UniProt ID
P48145
Chromosome Location
8p22-q21.13
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
Function
G-protein coupled receptor activity; opioid receptor activity; protein binding; receptor activity; signal transducer activity;

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